What is the significance of fever and pyelonephritis

What is the significance of fever and pyelonephritis?  Many times these patients will present as septic, what is sepsis criteria?  Why is it important to rule out and treat sepsis early?

How can you distinguish between pyelonephritis and a lower urinary tract infection?

When would hospital admission be appropriate for this patient?

What would your treatment plan include for this patient

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